The question “how long does kratom last in your system” mainly arises when kratom enthusiasts are told about a drug test, whether for employment, probation, or just a random check. at work. Before giving you the explanation of the main question, there. It is important to first understand the basics of kratom.
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Why is kratom a substance of concern?
Kratom has a bad reputation because there is very little research on it. Although the Drug Enforcement Administration (DEA) has not listed it as a controlled substance, it is recognized as a substance of concern due to its stimulant properties which can mimic the actions of opiate drugs.
How does Kratom work?
Kratom contains an abundance of alkaloids of which two main ones are mitragynine and 7-hydroxymitragynine. These alkaloids act on mu and delta opioid receptors in the brain to provide opioid-like effects such as pain relief, increased energy, and a feeling of general well-being.
Once consumed, the effects start to kick in around 10-15 minutes after. These effects may peak 40 minutes after consumption if taken on an empty stomach or 60-90 minutes with a meal. If it comes in capsule form, it will naturally take longer to kick in or peak because the capsule takes time to break down.
What is the half-life of kratom?
Understanding the half-life of kratom is crucial in determining how long it takes kratom to exit your system. The half-life of a drug is defined as the time it takes to reduce its concentration by half, taking into account the average metabolism to break down the drug.
Since research on kratom is limited, the half-life of kratom is unclear. Based on animal models, mitragynine is thought to have a half-life of approximately 23-24 hours. This means that it takes almost a full day to eliminate 50% of the kratom in the body and around five to six days before the kratom is eliminated from the system.
For example, if a user takes a 10mg dose of kratom, it takes 24 hours for the body to eliminate half of it, leaving 5mg in the system. 48 hours after the first dose, 2.5 mg remains in the system, and 36 hours after the first dose, 1.25 mg remains in the system, and so on.
There is also evidence to suggest that those who consume kratom less frequently or at lower doses clear the substances faster compared to long-term or higher dose users.
Factors That Determine How Long Kratom Stays In Your System
Although the half-life of kratom is approximately 24 hours, several factors can affect how long kratom stays in the system. Some of these factors include:
As you would expect, body function slows down with age. This means that the elimination of substances such as kratom decreases as the body’s rate of metabolism is slower. For this reason, doses of kratom or other substances are often lower for people of older age. It’s safe to assume that people over 65 will have a longer half-life, which will cause kratom to stay in their system longer.
Some families may gobble down a lot of alcohol before getting drunk while others start getting drunk after just half a bottle of beer. Apart from the usual factors such as age and sex, another main factor is genetics. Likewise, some people have genetic markers and enzymes in the body that affect the rate of elimination of kratom.
The liver and kidneys are responsible for removing toxins and medications from your system. When the liver or kidneys are not healthy, they decrease the rate of elimination and cause the kratom to stay in the system longer.
Kratom alkaloids such as mitragynine are fat soluble. This means that those with a higher body fat percentage are more likely to retain kratom metabolites, while those with lower body fat tend to clear kratom from their system at a faster rate.
Taking kratom with a high fat meal can lead to faster absorption and could lead to reaching peak concentration levels. Hydration levels can also affect the rate of elimination of kratom, as drinking more water helps your body eliminate it faster.
The metabolic rate plays an important role in determining the rate at which drugs or other substances are broken down. Those with a faster metabolic rate will burn kratom faster than those with a slower metabolic rate.
As briefly mentioned earlier, kratom users who have developed a tolerance to kratom are usually long-term kratom users. In these people, the kratom may stay longer in the system because the body has become accustomed to it in the body.
Kratom detection time
Kratom can be detected once the effects have worn off. The higher the dose taken, the longer it stays in the system. Depending on usage level, it can stay in the system for up to nine days. The detection time in the system depends on the type of test used.
- Urine – Detection up to nine days.
- Blood – Detection up to nine days.
- Hair – Detection up to ninety days.
How long kratom stays in the system depends on several factors. Since the half-life of kratom is about 24 hours, it takes about a day for the body to eliminate half of the dose of kratom taken. This means that the higher the dose of kratom taken, the longer it will remain in your system. Different tests will provide varying times, with a hair test being able to detect the existence of kratom in the system much longer than other tests. Users should note that those who take kratom long-term will also keep it in the system longer.